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Monnose-Binding lectin (MBL) appears to play an important role in the immune system. The genetic polymorphisms in the MBL2 gene can result in a reduction of serum levels, leading to a predisposition to recurrent infection. The aim of this study is to investigate the influence of a polymorphism in codon 54 of the MBL2 gene on the susceptibility to Erythema Multiforme, Stevens-Johnson Syndrome and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome (EM, SJS and SJS/TEN overlap syndrome).

balkan medical journal/balkan medical journal

Investigation of Mannose-binding Lectin gene Polymorphism in Patients with Erythema Multiforme, Stevens Johnson Syndrome and Stevens Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Syndrome