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Several randomized clinical trials (RCT) have been conducted in recent years on the efficacy of biological disease-modifying antirheumatic drugs (bDMARD) in the treatment of rheumatoid arthritis (RA). However, systematic reviews (SR) on this topic still raise doubts about the real efficacy related to functional capacity and quality of life. This is an overview that summarizes the evidences generated by SR of RCT that compare treatments using bDMARD versus conventional disease-modifying antirheumatic drugs (cDMARD), considering functional capacity and quality of life of the patients with RA, as well as evaluating the methodological quality of the SR that have been published on this subject.

blucher medical proceedings

QUALITY OF LIFE AND FUNCTIONAL CAPACITY OF RHEUMATOID ARTHRITIS PATIENTS TREATED WITH BIOLOGICAL VERSUS CONVENTIONAL DISEASE-MODIFYING ANTIRHEUMATIC DRUGS : OVERVIEW OF SYSTEMATIC REVIEWS