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Protection of L-cysteine ethanoate (II) with trityl chloride (III) in DMSO led to IV in 74 % yield after 4 days. 4 Several benzoic esters derivatives (VI) were obtained from the coupling reaction between IV and benzoic derivatives acids using DCC as coupling reagent and CH2Cl2 or dimethylcarbonate (DMC) as solvents, under microwave irradiation. 5 The results obtained for these reactions are summarized in Table 1.

Microwave irradiation and DMC: a potent combination for the synthesis of 2-arylamino-3-tritylsulfanyl-propionic ethyl ester