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1. In special, addition of salts can promote changes in enzyme solvatation which leads to changes in its interaction with the substrate 2 . However, this approach is scarcely considered in biocatalytic reactions for preparative purposes. Herein, we describe the enzymatic kinetic resolution of methyl (RS)-2-methyl-4-oxopentanoate by a series of changes in the medium with merit to salt effect.

Enzymatic kinetic resolution of methyl 2-methyl-4-oxopentanoate