English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

The synthesis of aminoquinones and related compounds has attracted considerable attention, because they exhibit a wide spectrum of pharmaceutical activities including antitumor and antimalarial properties 1 . Two general methods are available for the synthesis of aminoquinones 2 : nucleophilic substitution reaction of halo-derivative quinones with amines and direct 1,4-type addition of amines to quinones, with or without Lewis acid conditions under ultrasonic irradiation. As part of an ongoing research program on the synthesis of new quinone derivatives and on the basis of our experience in the field of the use of carbohydrates in organic synthesis, we herein report an extension of the second approach 3 which led to three novel isoquinoline-5,8-quinone derivatives 1a-c, possessing a carbohydrate chain at C-7position of the quinone ring.

The Ultrasound-accelerated Synthesis of New 7- Aminocarbohydrate-isoquinoline-5,8-quinone Derivatives