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This study involved collection of Ricinus communis leaves and seeds from Diyala, then prepared R. communis leaves by drying and grinding by electrical grinder and put in glass container for extraction which was carried out by Magnetic stirrer with methanol to extraction. Extract of R. communis form was pasty with dark green in color. While the R. communis seeds are collection and removed the cover of it, then squeezing by mechanical squeezing to remove the oil and take out only castor seed cake and extract by petroleum ether and drying with Sodium hydroxide (NaOH) that give powder white in color called bean cake extract. The pilot study was done to determine the range of dose which used in experiment by using two mice for each dose and each extract. The doses of leave extract were started with (100mg/kg) which was given to two mice orally by stomach tube the volume of dosing was (100 ml) the dosing was calculated according to the weight of mice, the doses (200 mg/kg), (400 mg/kg), (800 mg/kg), (1000 mg/kg), (1200 mg/kg), (1400 mg/kg) and (1600 mg/kg), the dose that kill the animal is (1250 mg/kg). While the doses of bean cake extract with methanol were started with (100 mg/kg) which given to two mice the volume of dosing was (100 ml) according to the weight of mice. The doses (200 mg/kg), (400 mg/kg), (1600 mg/kg), (3200 mg/kg), (4000 mg/kg), (5000 mg/kg) and (5200 mg/kg), the dose that kill the mice is (5200mg/kg). The doses of bean extract by petroleum ether were started with (10mg/kg) was calculated according to the weight of mice. The doses (10 mg/kg), (20 mg/kg), (40 mg/kg), (80 mg/kg), (100 mg/kg), (120 mg/kg), (140 mg/kg) and (160 mg/kg) and the dose that kill the mice is (150 mg/kg). Keyword: Ricinus Communis, Toxicity, LD50

TOXIC EFFECTS OF ALCOHOLIC EXTRACT OF LEAVES AND SEEDS OF RICINUS COMMUNIS IN MICE