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Protein kinase-C (PKC) and NF-kappaB are involved in cell survival, proliferation, migration and radioresistance in glioblastoma multiforme (GBM). We sought to determine the interaction between PKC and NF-kappaB pathways.

Pkc alpha phosphorylates cytosolic nf-kappab/p65 and pkc delta delays nuclear translocation of nf-kappab/p65 in u1242 glioblastoma cells