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The mechanism of action of intratumoral ethyl alcohol injection is dehydration and subsequent necrosis, denaturing the structure of the cellular proteins, resulting in complete ablation of the tumor. Pure alcohol also blocks blood flow to the tumor bed resulting in small blood vessel thrombosis that leads to tumor necrosis. Ethyl alcohol injection is also used for the treatment of liver and kidney tumors and vascular malformations (1).

Concern and usefulness of intratumoral injection of ethyl alcohol for devsacularization of intracranial tumors