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Despite advances in maxillofacial surgery, impaired bone healing remains a concern for surgical teams. Many studies have evaluated the effects of sildenafil and pentoxifylline on bone healing. However, their effects on healing of bone fractures have not been well investigated. This study aimed to assess the effects of the phosphodiesterase inhibitors sildenafil and pentoxifylline on healing of mandibular fractures in rats.

journal of the korean association of oral and maxillofacial surgeons/journal of the korean association of oral and maxillofacial surgeon/daehan gu'gang ag'anmyeon oe'gwa haghoeji

The effect of two phosphodiesterase inhibitors on bone healing in mandibular fractures (animal study in rats)