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Production of β-glucan is mainly used for cancer therapy. The most well-known are those occur in fungal grains such as cereal and other micro-organisms. The most important beta glucan from a nutritional and ingredient standpoint is that derived from fungal grain. Optimization of medium ingredients for the production of mycelial β-glucan from lower fungi in submerged fermentation and antioxidant activity of β-glucan was carried out.

Optimization of ?-Glucan Production from Lower Fungi using Central Composite Design and its Biological Application