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Isomeric pterocarpans, Dolichin A and Dolichin B of Macrotyloma uniflorum were docked with the three replication enzymes of HIV (Reverse transcriptase, Protease, Integrase). Analysed results proved that the docking score was high for Protease with Dolichin A (-6.6899) and Dolichin B (6.6944) among Reverse transcriptase and Integrase. AIDS therapies could be scrutinized and /or replaced after the successful inihibitory effect of Dolichin. This study will support the cutting edge of HIV research and drug designing to find out a less side effect causing herbal formulations.

Molecular Docking Studies of Dolichin A and B, Pterocarpans from Horsegram (Macrotyloma uniflorum) against HIV Replication Enzymes