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To understand Working of Human Brain measurements related to the brainfunction are required. These measurements should be possibly non-invasive.Brain should be disturbed as less as possible during the measurement.Integration of various modalities plays a vital role in understanding thecognitive and the behavioral changes in the human brain. It is an importantsource of converging evidence about specific aspects of neural functions anddysfunctions under certain pathological conditions. Focal changes in corticalblood flow are tightly coupled with the changes in neuronal activity. Thisconstitutes the option to map the hemodynamic response and infer principles ofthe cortical processing, even of complex tasks. The very high temporalresolution of EEG and good spatial resolution by NIRS make this concurrentmeasurement unique to study the spatio-temporal dynamics of large scaleneuronal networks in the human brain. Such integration of two techniques willhelp to overcome the limitations of a specific method. Such as insensitivity ofelectroencephalogram (EEG) to unsynchronized neural events or lack of nearinfrared spectroscopy (NIRS) to low metabolic demand. A combination of EEG andNIRS will be more informative than the two separate analyses in bothmodalities.

Human Brain Mapping based on COLD Signal Hemodynamic Response and Electrical Neuroimaging