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Increased Raf-1 expression has been associated with an aggressive behaviour in some carcinomas such as pulmonary carcinoma and renal carcinoma. However, its role in breast cancer, especially in basal-like carcinoma of the breast (BLBC), has not been defined.

Overexpression of Raf-1 in basal-like carcinoma of the breast: correlation with clinicopathology and prognosis