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This study aimed to evaluate 8-OHdG and hypoxia-inducible factor 1 (HIF-1α) levels in patients with hypoactive thyroid nodules (toxic multi-nodular goiter, Graves' disease, and Hashimoto's thyroiditis), as these parameters may be related to oxidative stress and the pathogenesis of cancer.

Serum 8-OHdG and HIF-1 levels: do they affect the development of malignancy in patients with hypoactive thyroid nodules?