English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Aim: The aim was to assess the impact of impaired renal function on myocardial tissue reperfusion in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (pPCI). Material and methods: Impaired renal function was diagnosed at admission based on abnormal serum creatinine level (> 106 μmol/l). Patients with anterior STEMI and maximal single-lead ST-elevation (maxSTPost) exceeding 2 mm up to 90 min post-procedure, as well as patients with inferior STEMI and maxSTPost > 1 mm, were considered to have failed tissue reperfusion. The incidence of death or heart failure (NYHA class > 2) was prospectively assessed over a subsequent 12-month period. Results: Primary PCI and maxSTPost measurements were performed in 200 out of 208 consecutive patients (63.0 ±12.1 years, 67.5% males) treated between October 2007 and September 2008. Patients with impaired renal function (12.5%) died or developed heart failure more often when compared to the remaining individuals (56.0% vs. 16.0%, p < 0.001, respectively). Patients with failed reperfusion (15.5%) had higher incidence of one-year mortality and heart failure (35.5% vs. 18.3%, p = 0.032, respectively). Failed tissue reperfusion was 2.5 times more frequent among patients with impaired renal function, despite a relatively high rate of final TIMI 3 flow as compared to the remaining subjects (32.0% vs. 13.1%, p = 0.022 and 84.0% vs. 92.6%, p = 0.239, respectively). Impaired renal function and failed reperfusion were independent predictors of death or heart failure (odds ratio (OR) = 4.38, 95% confidence interval (CI) 1.34-14.28, p = 0.014, and OR = 3.34, 95% CI 1.12-9.88, p = 0.029, respectively). Impaired renal function was a risk factor for failed tissue reperfusion (OR = 2.98, 95% CI 1.03-8.68, p = 0.044). Conclusions: Impaired renal function in patients with STEMI treated with primary PCI is related to the risk for failed myocardial tissue reperfusion, leading in consequence to higher one-year mortality and heart failure.

postępy w kardiologii interwencyjnej

Impaired renal function in patients with myocardial infarction treated with primary angioplasty and the risk for failed myocardial tissue reperfusion and thus worse long-term outcomes