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Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects primarily preterm infants. Genetic factors are also taken into consideration in the pathogenesis of BPD. Genetic predispositions to higher production of inflammation mediators seem to be crucial.

central-european journal of immunology/central european journal of immunology

The significance of IL-1β +3953C&gt;T, IL-6 -174G&gt;C and -596G&gt;A, TNF-α -308G&gt;A gene polymorphisms and 86 bp variable number tandem repeat polymorphism of IL-1RN in bronchopulmonary dysplasia in infants born before 32 weeks of gestation