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Corresponding authors: Dr. Xingshun Qi Prof. Xiaozhong Guo Department of Gastroenterology General Hospital of Shenyang Military Area Shenyang, 110840 China Phone: +86 24 28897603 Fax: +86 24 28851113 E-mail: xingshunqi@126.com, guo_xiao_zhong@126.com 1 Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, Shenyang, China 2 Department of General Surgery, General Hospital of Shenyang Military Area, Shenyang, China

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