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Alkenes, alkanes, and polystyrene were converted into fully deuterium labelled ones by treatment with transition metal catalyst and deuterium oxide under hydrothermal condition. The simple method to get fully deuterium labelled compounds is easy to apply to various types of organic compounds.

yūki gōsei kagaku kyōkaishi/yuuki gousei kagaku kyoukaishi

Story Concerning about Autoclave -H-D Exchange Reaction of Organic Compounds in Deuterium Oxide under Supercritical Condition, Hydrothermal Condition, or Microwave Irradiation.