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All-trans retinoic acid (ATRA)/anthracycline chemotherapy is beneficial in newly diagnosed acute promyelocytic leukemia (APL); however, it is important to identify patients with high-risk disease to increase the cure rate. We investigated the outcome of ATRA/anthracycline chemotherapy and clinicobiological correlations of FLT3/ITD and NPM1 mutations in APL patients.

the korean journal of hematology

Treatment outcome of all-<i>trans</i>retinoic acid/anthracycline combination chemotherapy and the prognostic impact of<i>FLT3</i>/ITD mutation in acute promyelocytic leukemia patients

Treatment outcome of all-transretinoic acid/anthracycline combination chemotherapy and the prognostic impact ofFLT3/ITD mutation in acute promyelocytic leukemia patients