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The F8 and F9 genes encode for coagulation factor VIII (FVIII) and FIX, respectively, and mutations in these genes are the genetic basis of hemophilia A/B. To determine whether a sequence variation in F8/F9 is a disease-causing mutation, frequency data from a control population is needed. This study aimed to obtain data on sequence variation in F8/F9 in a set of functionally validated control chromosomes of Korean descent.

blood research

Sequence variation data of<i>F8</i>and<i>F9</i>genes in functionally validated control individuals: implications on the molecular diagnosis of hemophilia

Sequence variation data ofF8andF9genes in functionally validated control individuals: implications on the molecular diagnosis of hemophilia