English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

A radioterapia e uma das terapias mais empregadas em lesoes malignas de cabeca e pescoco, podendo esta associada ou nao a outras modalidades terapeuticas cirurgia e quimioterapia. Entretanto esta terapia pode interferir na qualidade de vida dos pacientes, podendo alterar a evolucao do tratamento devido a efeitos colaterais indesejaveis como mucosite, xerostomia, disgeusia, dermatite, candidose. O presente estudo objetiva avaliar a microbiota bucal de pacientes submetidos a radioterapia para tratamento de lesoes malignas de cabeca e pescoco. A amostra constituiu de 51 pacientes numa instituicao privada de radioterapia de Sao Jose do Rio Preto-SP. Os pacientes foram avaliados em tres momentos, antes de iniciar a radioterapia, preenchendo a ficha clinica que incluia dados socio demograficos, avaliacao dentaria e periodontal; no segundo momento avaliava as alteracoes bucais e peribucais decorrentes da radioterapia entre 15 e 22 dias; e terceiro momento, no qual esses pacientes foram avaliados imediatamente apos a conclusao da terapia. Em todas essas fases os especimes coletados foram biofilme supragengival, biofilme subgengival, mucosa lisa, dorso de lingua, alem de amostras de saliva, os quais foram detectados por PCR. Os microrganismos avaliados foram A. actinomycetemcomitans, F. nucleatum, P. micra, P. gingivalis, P. intermedia, P. nigrescens, T. forsythia, T. denticola e leveduras do genero Candida. A ocorrencia de complicacoes agudas, como xerostomia e mucosite em decorrencia da radioterapia alterou significativamente os microrganismos anaerobios Gram-negativos estudados e leveduras do genero Candida, exceto P. nigrescens e A. actinomyctemcomitans. A higiene bucal regular dos pacientes irradiados contribuiram com a proliferacao dos microrganismos facilitando a adesao microbiana na saliva e mucosa. Conclui-se que a participacao do odontologo e fundamental para o controle quimico do biofilme, dieta, higiene bucal proporcionando melhor qualidade de vida desses...(AU) Radiotherapy is one of the most widely used therapies in malignant head and neck can is not associated with other treatment modalities surgery and chemotherapy. However, this therapy can interfere with quality of life of patients and may alter the course of treatment due to side effects such mucositis, xerostomia, dysgeusia, dermatitis, candidiasis. This study aims to evaluate the oral microbiota of patients undergoing radiotherapy for treatment of malignant head and neck. The sample consisted of 51 patients in a private institute of radiotherapy, Sao Jose do Rio Preto-SP. Patients were evaluated three times, before starting radiotherapy, filling the medical records that included socio demographic data, dental and periodontal evaluation, in the second moment evaluated the oral and perioral changes caused by radiotherapy between 15 and 22 days and third time in which these patients were assessed immediately after the completion of therapy. In all these stages the specimens were collected supragingival biofilm, subgingival biofilm, flat mucosa, tongue, and saliva samples, which were detected using PCR. The microorganisms evaluated were A. actinomycetemcomitans, F. nucleatum, P. microns, P. gingivalis, P. intermedia, P. nigrescens, T. forsythia, T. denticola, and Candida spp. The occurrence of acute complications such as xerostomia and mucositis due to radiotherapy significantly alter the anaerobic microorganisms studied Gram-negative and Candida species, except P. nigrescens and A. actinomyctemcomitans. Regular oral hygiene of patients irradiated contributed to the growth of microorganisms to facilitate microbial adhesion in saliva and mucous. Conclude that the participation of the dentist is essential for chemical control of biofilm, diet, oral hygiene by providing better quality of life of these patients reducing opportunistic infections that arise during radiotherapy(AU)

Influência da radioterapia para tratamento de lesões malignas de cabeça e pescoço sobre a ocorrência de microrganismos bucais