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. In the present work we described oxidative cyclisation of peracetylated lactosyl carbamides with N -phenyl- S -chloroisothiocarbamoyl chloride and structural elucidation of novel peracetylated N -Lactosyl-1,2,4-Thiadiazolidin-3-one hydrochlorides. Antimicrobial activities of the title compounds were determined against bacteria S. aureus , E. coli , P. Vulgaris , P. Aeruginosa and fungi A. Niger , Penicillium . Keywords: Peracetylated lactosyl carbamides, Isothiocarbamoyl chloride , Cyclisation, Peracetylated lactosyl thiadiazolidin-3-one, Synthesis, Antimicrobial activity Peracetylated N -Lactosyl-1,2,4-Thiadiazolidin-3-one Hydrochlorides:    Anvita S. Dandale † , Dattatraya V. Mangte, and Shirish P. Deshmukh * P. G. Department of Chemistry, Shri Shivaji College, Akola-444001 (M.S.) India † Dept. of Applied Chemistry, Faculty of Tech. & Engg., The M. S. University of Baroda, Vadodara-390001, Gujarat, India ( 2009. 12. 1;  2010. 3. 28;  2010. 4. 6) Novel Peracetylated

Novel Peracetylated N-Lactosyl-1,2,4-Thiadiazolidin-3-one Hydrochlorides: Synthesis and Antimicrobial Studies