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, the first AChE inhi-bitor), donepezil, rivastigmine, and galanthamine are available for AD treatment. However, the use of AChE inhibitors is sometimes limited mainly due to serious adverse effects such as hepatotoxicity and modest benefits to AD patients. Efforts to search for more potent and selective inhibitors of AChE without side effects still remain highly significant in AD treatment. Recently, we have reported the synthesis of new thienopyridine derivatives

Synthesis of 10-Amino-5,6,7,9-tetrahydro-1-thia-4,9-diazacyclohepta[f]inden-8-one Derivatives using Schmit Reaction