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E-mail: kyslee@khu.ac.krReceived April 15, 2013, Accepted May 16, 2013Key Words : Baicalein, 5,6,7-Trimethoxyflavone, Sulfonamide, Cytotoxicity, Cancer cell lineThe root of Scutellaria baicalensis Georgi have beentraditionally used clinically in China, Korea and Japan totreat various ailments, such as allergy, inflammatory disease,diarrhea, and infections accompanied by fever. Studies havealso reported that the extract from S. baicalensis ex-hibits antifungal activity,

Synthesis and Cytotoxic Effects of Sulfonamide-Substituted 5,6,7-Trimethoxyflavones on Human Cancer Cell Lines