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One of thesesequences, an 18-mer containing four guanine-tracts, 5'-GGGAGGGGCGGGUCUGGG-3' is associated with the 5'-UTR of the oncogenic N-ras sequence. According to a cell-free translation system coupled to a reporter gene assay, theN-ras G-quadruplex can inhibit gene expression at thetranslational level.

Identification of a Conserved Sequence Motif of an RNA Aptamer Binding to a G-rich Sequence RNA with Structural Probes