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Institute of Pharmacy, Nirma University, S. G. Highway, Ahmedabad-382481, IndiaReceived November 7, 2011, Accepted November 29, 2011Key Words : Biginelli reaction, 3,4-Dihydropyrimidinones, Silica-gel, Multi-component reactionThe pyrimidinone ring is a basic substructure of numerousbiologically active alkaloids and pharmaceutical products.

Silica-gel Catalyzed Facile Synthesis of 3,4-Dihydropyrimidinones