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Department of Biochemistry and Biomedical Sciences, Seoul National University College of Medicine, Seoul 110-799, KoreaReceived August 8, 2012, Accepted August 27, 2012Key Words : mPTP, Cyclophilin D, Alzheimer’s disease, Pyridyl-urea, ATP productionAlzheimer’s disease is a progressive neurodegenerativedisorder in aged people and the pathogen is known asamyloid beta (A β) with different slicing.

Pyridyl-urea Derivatives as Blockers of Aβ-induced mPTP Opening for Alzheimer's Disease