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Sodium periodate () and potassium iodide (KI) in aqueous ammonia has been used for the one-pot synthesis of nitriles from the corresponding aldehydes and alcohols in moderate to good yield. This transformation, proceeds via an in situ oxidation- imination-aldimine oxidation sequence.

A Simple and One-pot Oxidative Conversion of Alcohols or Aldehydes to the Nitriles using NaIO4/KI in Aqueous NH3

A Simple and One-pot Oxidative Conversion of Alcohols or Aldehydes to the Nitriles using NaIO₄/KI in Aqueous NH₃