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Center for Marine Natural Products and Drug Discovery, School of Earth and Environmental Sciences, Seoul National University, NS-80, Seoul 151-747, Korea Research Institute of Oceanography, Seoul National University, Seoul 151-741, Korea *E-mail: jwchin97@snu.ac.kr (J. Chin); hjkang@snu.ac.kr (H. Kang) Korea Institute of Science and Technology, Gangneung Institute, Gangneung 210-340, Korea Received August 16, 2011, Accepted September 15, 2011

Synthesis of an Urea-substituted Selenoisobutyric Acid Isostere of the Peroxisome Proliferator-activated Receptor α Selective Agonist