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on melanogenesis in melan-a cells. Test sampleswere tested at three concentrations of 1, 10 and 100 µg/mL. PTU (1-phenyl-2-thiourea) was used as positive control. Test sample and medium were renewed daily. The cell viabilities and the melanin con-tents of melan-a cells were determined after 3 days. Inhibitory activityof melanogenesis and the effect of cell viability were expressed as a percentage of the control. The data shown represent the means ± SD of three independent experiments performed in duplicate.

Anti-melanogenic Fatty Acid Derivatives from the Tuber-barks of Colocasia antiquorum var. esculenta