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Progesterone (pregn-4-ene-3,20-dione) is a C-21steroid hormone involved in the female reproductive systems and embryogenesis of humans and other species and consists of four interconnected cyclic hydrocarbons (Figure 1a). It is also an important drug used clinically to treat advanced ovarian, breast and non-small cell lung cancers.

Electrospray Ionization Mass Spectrometric Analysis of Noncovalent Complexes of Hydroxypropyl-β-cyclodextrin and β-Cyclodextrin with Progesterone