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and their com-plexes with metal ions show a better stability than acyclo-chelating agents. However, despite their good properties, forming a metal complex demands an incubation of about 0.5 hr ~ 2 hrs, and, at times, a high temperature. Therefore, we have concentrated on the development of new BFCAs which have a higher affinity and stability to almost all kinds of lanthanides ions using diethylene triamine pentaacetic acid (DTPA). We previously reported on a synthetic method for DTPA derivatives whose original moiety are intact by using cysteine.

Synthesis of Bifunctional Chelating Agent Derived from Lysine and its Radiolabeling with99mTc

Synthesis of Bifunctional Chelating Agent Derived from Lysine and its Radiolabeling with^99mTc