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APRIL, Angiogenesis, Vascular endothelial growth factor (VEGF)Angiogenesis, the generation of new capillary blood vesselsfrom pre-existing vessels, occurs under normal and patho-logical conditions. Although angiogenesis in physiologicalprocesses is tightly regulated by a balance of stimulatoryfactors and inhibitory factors, disrupted balance effect playsa leading role in the progress of diseases such as tumorgrowth, rheumatoid arthritis and various blood vessel-related pathology.

A Proliferation-inducing Ligand (APRIL) Acts as an Angiogenic Factor by Inducing Vascular Endothelial Growth Factor (VEGF)