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Consequently,exact determination of the enantiomeric composition of 3-substituted 1,4-benzodiaepin-2-ones is very important.Among various methods, liquid chromatographic separationof enantiomers on chiral stationary phases (CSPs) are gener-ally known as the most accurate, convenient and economicmeans for the determination of enantiomeric composition ofchiral compounds and, consequently, various CSPs havebeen developed.

bulletin of the korean chemical society

Liquid Chromatographic Resolution of Racemic 1,4-Benzodiazepin-2-ones on a Chiral Stationary Phase Based on N,N'-Bis-(3,5-dinitrobenzoyl)-2,3-diamino-1,4-butandiol