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we found that simple modification of functionalgroups on C2, C3, C23 or C28 groups on asiatic acid greatlyaffected the hepatoprotective activities. It would be veryinteresting to prepare the modified derivatives on C2, C3,C23 and C28 functional groups on asiatic acid and evaluatehepatoprotective effects of the prepared compounds. Inaddition, structure-activity relationship studies of the pre-pared derivatives may provide valuable information for thedevelopment of novel hepatoprotective agents. In connec-tion with previous studies, C2, C3, C23 and C28 functionalgroups on asiatic acid were modified and evaluated for theirhepatoprotective effects.

Modification of C2,3,23,28 Functional Groups on Asiatic Acid and Evaluation of Hepatoprotective Effects