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a general synthetic route to 1 and itsstructural relatives was anticipated to develop for theexpansion of the structural diversity of this privilegedstructure. Though several preparative routes to 1 werereported, structural or positional variation in the constructionof spiro-heterocyclic compounds was limited since all thereported synthetic routes to 1 started from 4-substitutedpiperidines

A Sequential Cyclization Route to Spiroindanyl Heterocycles through Olefin Metathesis and Free Radical Reaction