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Department of Chemistry, Dongeui University, Busan 614-714, KoreaReceived July 19, 2004Key Words : N-Benzoyl-4(5)-methylimidazole, Bifunctional catalyst, pH-rate profile, CatalysisAcetate, cacodylate, phosphate and imidazole are wellknown as the bifunctional acid and base catalysts. Catalysisof these bifunctional catalysts depends on the structure of thereaction substrates. For example, in nucleophilic substitutionreaction at the carbonyl carbon, imidazole has been found tobe 100-4000 fold as reactive as phosphate dianion,

Influence of Bifunctional Catalysts in the Hydrolysis Reactions of N-Benzoyl-4(5)-methylimidazoles