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Research Institute of Industrial Technology, Kyungpook National University, Taegu 702-701, KoreaDepartment of Industrial Chemistry, College of Engineering, Kyungpook National University, Taegu 702-701, KoreaReceived January 15, 2002Keywords : Nitroarenes, Quinolines, Reduction, Ruthenium, Tetraalkylammonium bromides.It is known that several quinoline containing compoundsexhibit pharmacological activity for malaria. The quinolineskeleton is generally constructed by conventional namedroutes such as Skraup, Dobner-von Miller, Conrad-Limpach,Friedlaender and Pfitzinger syntheses.

Ruthenium-Catalyzed Consecutive Reduction and Cyclization of Nitroarenes with Tetraalkylammonium Bromides Leading to Quinolines