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and Hyun ParkDepartment of Chemistry, College of Natural Science, Duksung Women's University, Seoul 132-714, Korea Received November 17, 2001Keywords : N-Methoxy-N-methylamide, Bis(trichloromethyl) carbonate, N,O-Dimethylhydroxylaminehydrochloride, N-Methoxy-N-methylcarbamoyl chloride.The N-methoxy-N-methylamides (Weinreb amides) havebeen widely used as effective carbonyl equivalents sincethey react with organometallics to provide various carbonylfunctional groups through very stable metal-chelated inter-mediates.

An Efficient Synthesis of N-Methoxy-N-methylamides from Carboxylic Acids Using N-Methoxy-N-methylcarbamoyl Chloride