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Hypoxia-inducible factor-1alpha (HIF-1alpha) is a mediator of tumor progression. Vascular endothelial growth factor (VEGF) is the most potent angiogenic factor known to be induced by HIF-1alpha. We investigated the clinicopathological significance of HIF-1alpha and VEGF levels in biopsied gastric cancer tissue.

The Clinicopathological Significance of Tissue Levels of Hypoxia-Inducible Factor-1α and Vascular Endothelial Growth Factor in Gastric Cancer