English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Aims: The aim of the study was to show a simultaneous increase of high sensitive C-reactive protein (hs-CRP) with a degree of renal involvement suggested by albumin-creatinine ratio and dyslipidemia in diabetic patients, as the period of diabetes progresses. No such duration based study has ever been conducted so far in the sub-Himalayan region and fringe area including different ecosystem as in the present study. Materials and methods: It was an Institution based observational comparative study conducted in a tertiary care hospital in sub-Himalayan belt from April 2016 to March 2017 among 120 diabetic individuals aged (30–60) years irrespective of gender, divided into 3 groups of 40 subjects in each, namely: (a) newly diagnosed <5 years, (b) 5–10 years after diagnosis and, (c) ≥10 years after diagnosis. Research variables were hs-CRP, urinary ACR and lipid profile. Results: Descriptive studies showed that mean values of hs-CRP were 0.04 ± 0.005, 0.08 ± 0.011, and 0.10 ± 0.017 and that of ACR were 100.29 ± 11.59, 117.65 ± 6.93 and 128.80 ± 7.91 in groups 1, 2, 3, respectively. One-way analysis of variance (ANOVA) with post hoc analysis after Bonferroni correction between different groups enunciated that both hs-CRP and ACR increased significantly and statistically (p <0.001) with a duration of diabetes in all three groups unlike the parameters of lipid profile. Hs-CRP, ACR, cholesterol and LDL even illustrated a very significant correlation between each other (p <0.001) whereas TG and HDL have shown correlations neither to themselves nor other parameters. Conclusion: Early detection, monitoring of inflammatory markers hs-CRP and ACR as predictors of diabetic nephropathy can help in modulating diabetes and its complications.

indian journal of medical biochemistry/indian journal of medical biochemistry

Association of Serum Hs-CRP with Urinary Albumin Creatinine Ratio and Lipid Profile in Diabetic Individuals Attending a Tertiary Care Hospital in the Sub-Himalayan Belt