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Vitiligo is one of the common depigmentary disorders that remains one of the major dermatological challenges worldwide, especially in India.1 It affects approximately 3 to 4% in India2 and 1% of the world’s population and affects all races.3 In view of multiple hypotheses behind the pathogenesis of vitiligo, proper treatment modality has not been established. The response to medical line of treatment is 30%. Surgical management may be the ray of hope in remaining patients if the vitiligo is stable. Stable vitiligo amenable to surgical modality of treatment depends on the site, age, and stability of the disease.3 For the past one decade, NECS has gained popularity because of superior esthetic results, requirement of only smaller donor area, and suitable to treat difficult areas. During the last 2 to 3 years, many modifications have been attempted to simplify the procedure and to get better outcome.4 Conventional reagents used include trypsin ethylenediaminetetraacetic acid (EDTA), trypsin inhibitor, DMEM. However, limitation of NECS technique is the high cost of these reagents. Animal sera, especially fetal bovine serum, are an important constituent of most melanocyte culture media and are believed to be rich in melanocyte growth factors.5 Hence, use of human serum instead of conventional reagents as a suspension medium for noncultured melanocytes would give equal or better results. Recent literature has shown usage of patient’s own plasma as an alternative to DMEM.5,6 The PPP also has trypsin inhibitor property.7 With this background, in this study, we attempted to replace two expensive reagents namely trypsin inhibitor and DMEM with patient’s own PPP in NECS surgery in the treatment of stable vitiligo, which may be costeffective and beneficial for our vitiligo patients.

A Study on Effectiveness of Platelet-poor Plasma as a Media in Autologous Noncultured Epidermal Cell Suspension in the Treatment of Stable Vitiligo