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Medications have been widely used in the dental patients for the treatment of their systemic diseases. In fact, those drugs have some side-effects to many organs and also the oral cavity. The aim of our study was to investigate the relationship between medications and oral lichen planus (OLP), oral lichenoid drug reaction (OLDR) and glossitis (GT) in Thai patients. Materials and methods: One hundred and thirty-eight cases of Thai patients were included in this study. Medical records of all cases with oral lesions and symptoms referred to the oral medicine clinic during 2007 to 2010 were extracted. Oral lichen planus group consisted of 88 cases, GT 26 cases and OLDR 24 cases. All data were analyzed using SPSS for Windows version 11.5. Results: In our study, 75.5% of patients used more than one medication while single drug used was 24.5%. Antihypertensive drugs were the most commonly used in all groups. Antihypertensive and hypolipidemic drugs were equally taken 22.4% in OLP patients. Patients with OLDR taking antihypertensive in 54.2% followed by hypolipidemic (37.5%), NSAIDs (25%), hypoglycemic/antiplatelet (16.7%) each and others 25%. Patients in GT group were also used antihypertensive drugs 35%, NSAIDs 25%, hypolipidemic 20% respectively. Conclusion: Most of patients with oral lesions took more than one medication. Antihypertensive drugs were the most commonly used in Thai patients with oral lesions.

Medications in Thai Patients with Oral Lichen Planus, Oral Lichenoid Drug Reaction and Glossitis