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Pharmacovigilance refers to the science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problems. During the pharmacovigilance activities undertaken by us, a case of toxic epidermal necrolysis provided us with a setting for discussing various aspects of pharmacovigilance—the process itself, important signal generators that it may yield for practice, research and policy-related matters.

A Case of Drug-induced Toxic Epidermal Necrolysis: Pharmacovigilance in Action and Lessons to learn