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Eating pan masala (PM), a product without betel leaf, currently, is a very popular habit among Indians. Aggressive marketing and high profile advertising developed inclination and addiction even among school children, youth, and labors and in various occupations just to elevate their mood and psychoenlightenment. Generally, it contains betel nut, catechu (kattha) and lime as major ingredients, flavorings and exotic spices. Betel nut and catechu were found toxic.1-4 However, consumption of this mixture causes more toxicity than the individual components of PM alone. The present study deals with hepatotoxicity of 2% plain and tobacco blended PM mixed in diet for prolonged duration in mice.

Effects of Plain and Blended Indian Pan Masala on Murine Liver