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Aim: To assess ovarian reserve, in infertile women with genital tuberculosis, planning to undergo in vitro fertilization (IVF) and to compare it with infertile women without genital tuberculosis, planning to undergo IVF. Materials and methods: The study group consisted of 100 women with genital tuberculosis and the control group of 100 women who had no present or past history of tuberculosis. A diagnosis of genital tuberculosis was made based either on the results of tests performed from an endometrial aspiration sample or on histopathologic, hysterosalpingography, hysteros­ copy, or laparoscopy findings. Basal ovarian reserve studies included measuring serum levels of follicle­stimulating hormone (FSH), luteinizing hormone (LH), and E2 on day 3 of a natural cycle. On the same day, the participants underwent a transvaginal ultrasound examination by means of a two­dimensional 5.0 MHz probe fitted to a Toshiba Famio 5. Ovarian volume and number of antral follicles were estimated for each ovary on the same day of hormonal assessment. Control participants underwent the same tests on day 2 or 3 of their menstrual cycle. Unpaired or independent t­test and Chi­square test were used for sta­ tistical analysis. Results: The present study highlights that women with genital tuberculosis have poor ovarian reserve in comparison to women of similar age without tuberculosis. Conclusion: It can be concluded that there is no single abso­ lute method of assessing ovarian reserve, but a combination of methods can closely predict the outcome of IVF cycles in women with genital tuberculosis.

Effect of Tuberculosis on Ovarian Reserve of Patients undergoing in vitro Fertilization