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Aim: To evaluate the prognostic value of first postembryotransfer beta human chorionic gonadotropin (hCG) levels inpregnancy outcome in an assisted reproductive technology(ART) program.Subjects: Seventy-one women with an initial beta-hCG valueof greater than 5 mIU/ml postembryo transfer in the ARTprogram were taken in to the study. The beta-hCG test wasdone 14 days after embryo transfer. The period of study wasfrom January 2008 to August 2010.Observations: A significant correlation was found in beta-hCGvalues between viable and nonviable pregnancies. In womenwho had a day 2 embryo transfer the mean beta-hCG valuewas 608 ± 580 mIU/ml, in comparison to women who had aday 5 transfer 1,527 ± 2,024 mIU/ml, and this was statisticallysignificant.Women who had a single embryo transfer had a mean betahCGlevel of 168 mIU/ml, two embryos 464 mIU/ml and threeembryos 612 mIU /ml.Mean beta-hCG value was highest in women who developedgestational diabetes [2,074 mIU/ml] women with pregnancyinducedhypertension (PIH) had a mean beta-hCG value of674 mIU/ml, and with antepartum hemorrhage the value waslower 220 mIU/ml.Conclusion: To summarize, beta-hCG level is an useful markerfor prognosticating early pregnancy well being, for predictingmultiple pregnancies. When interpreting the first beta-hCG leveluniformly after 2 weeks of embryo transfer, day of transfer ofembryos should be taken into account. The number of embryostransferred does not alter the beta-hCG level significantly. BetahCGlevel implications in pregnancy complications, likegestational diabetes (GDM), PIH, APH, require further researchand would be a useful tool for early screening and surveillanceof pregnancy.

First Postembryo Transfer Beta-hCG Level and Pregnancy Outcome in an Assisted Reproductive Technology Program