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Oral submucous fibrosis (OSF) is a betel quid habit associated with chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the oral and oropharyngeal submucosal tissues. It results in marked rigidity of the oral mucosa and an eventual decrease in the oral health-related quality of life due to the inability to open the mouth and burning sensation. In addition to significant morbidity, OSF has the highest malignant transformation rate and associated mortality.1 Among all the oral potentially malignant disorders, OSF was the most prevalent (4.96%; 95% CI = 2.28–8.62) pathology followed by leukoplakia (4.11%; 95% CI = 1.98–6.97). Due to the increase in betel quid consumption among the population, the prevalence rate for OSF is likely to increase in the near future. Since stage II and stage III are symptomatically more unbearable, the majority of these patients usually report to healthcare professionals at this stage. Despite the extensive research on pathogenesis and treatment, no standardized management protocol is still available and it varies from physician to physician.2 Moreover, pharmacological therapies need to be given for longer periods to minimize the symptoms in stage I to stage III patients. As no promising modality is still proved for the complete cure of OSF, careful monitoring with regular follow-up of these patients is essential. This is of utmost importance due to the high malignant transformation rate of OSF. With the coronavirus disease-2019 (COVID) pandemic, many of the healthcare professionals, institutions, and government agencies are paying the utmost attention to COVID-19 patients. As COVID19 is highly contagious and can spread via respiratory droplets, healthcare professionals, particularly dentists, otolaryngologists, ophthalmologists, and head and neck surgeons, are at a high risk of infection.3 As an effect of this and a lockdown, many of the patients who are already undergoing treatment for OSF find it difficult to reach to their healthcare professionals specialists for follow-up and treatment continuation. This is even more difficult for OSF patients residing in remote areas with limited healthcare facilities. Thus, there is a high probability of missing out on early detection of oral cancer in OSF patients leading to an advanced stage and poor prognosis. Although the whole world is going through COVID-19 pandemic, serious health concerns such as oral cancer cannot be overlooked at any cost. In the present paper, we have made an effort to discuss some of the options that can be potentially incorporated for the efficient delivery of health care in OSF patients. • Opportunistic oral cancer screening: Recently, it has been suggested that opportunistic oral cancer screening can be performed while COVID-19 throat swab collection to help identify malignant lesions especially in high-risk patients, such as OSF and leukoplakia.4 Although it seems a logical approach, it would address a very limited population that is visiting for check-ups and testing for COVID-19. Moreover, the availability of expert human resources for clinical diagnosis and management will be a major limitation for this kind of approach. In the current pandemic situation, it will be inappropriate to deviate the primary focus of COVID-19 testing and overburden frontline healthcare professionals who could be already under stress or depression. • Mouth self-examination: Studies have shown that the selfmouth examination strategy works very efficiently in screening the large population for oral potentially malignant disorders (OPMDs) and oral cancer.5,6 We believe that it would be an efficient tool for the early detection of oral cancer in OPMDs. However, this technique might not be effective for OSF patients due to limited mouth opening. This is especially true for stage III and IV patients where hindrance created by limited mouth opening interrupts thorough mouth self-examination. • Instant messaging services: Due to affordability, smartphones are widely used and have become part and parcel of daily life. Instant messaging services such as WhatsApp have commonly used applications by the majority of the population. Even the youth in rural areas are accustomed to the usage of smartphones and many commonly available instant messaging services. We believe that these can be used by OSF patients also for effective 1Department of Oral Medicine and Radiology, Government Dental College and Hospital, Nagpur, Maharashtra, India 2,5Department of Oral Pathology and Microbiology, Dr DY Patil Dental College and Hospital, Dr DY Patil Vidyapeeth, Pune, Maharashtra, India 3Department of Dentistry, Indira Gandhi Government Medical College and Hospital, Nagpur, Maharashtra, India 4Department of Oral Medicine and Radiology, College of Dental Sciences, Bhavnagar, Gujarat, India 6Independent Researchers, Nagpur, Maharashtra, India 7Department of Surgery, People’s College of Medical Science and Research Centre, People’s University, Bhopal, Madhya Pradesh, India Corresponding Author: Shailesh Gondivkar, Department of Oral Medicine and Radiology, Government Dental College and Hospital, Nagpur, Maharashtra, India, Phone: +91 9604121273, e-mail: shailesh_ gondivkar@yahoo.com How to cite this article: Gondivkar S, Sarode S, Gadbail A, et al. Telemedicine Approach for Oral Submucous Fibrosis in Coronavirus Disease-2019 Hot Spots. World J Dent 2020;11(4):253–254. Source of support: Nil Conflict of interest: None