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Aim: The present study was carried out with the objective of comparing the compressive strength and setting time of four experimental nanohybrid mineral trioxide aggregates (MTAs) and angelus MTA. Materials and methods: In this research, four experimental formulations of nanohybrid MTA (groups are with the base of Portland cement, containing nanoparticles of zirconia, aluminum oxide, titanium, nanosilica, and gypsum and bismuth trioxide) and angelus MTA were compared. Powder and water were mixed with the ratio determined by a factory for angelus MTA and were mixed at a ratio of 3:1 in experimental samples until the consistency of putty was reached. These were then placed in stainless steel cylinder generators, with a diameter of 4 mm and a height of 6 mm, for testing compressive strength, and in generators with a diameter of 10 mm and height of 2 mm to test setting time. The samples prepared were tested after 24 hours and a month using a strength-testing machine. A 135 G needle was used to test the initial setting time in the prepared samples, and a 456.5 G needle was used to test the final setting time. In the end, data were analyzed using Statistical Package for the Social Sciences (SPSS) software. Results: Experimental nanohybrid MTA P significantly showed the minimum setting time and experimental nanohybrid MTA Q showed the maximum setting time in 30 days (p < 0.05). Angelus MTA had greater compressive strength than the experimental materials in 24 hours. Conclusion: Experimental MTAs showed less setting time compared with the angelus MTA. Addition of nanoparticles in the Q group significantly affected the compressive strength of MTA. Compressive strength significantly increased over time in all groups. Clinical significance: Considering that experimental MTAs showed less setting time compared with the commercial type, experimental MTAs can be deployed in clinical usage. ORIGINAL RESEARCH 1Department of Operative and Esthetic Dentistry, Dental Research Center, Faculty of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Islamic Republic of Iran 2-4Department of Operative and Esthetic Dentistry, Faculty of Dentistry, Tabriz University of Medical Science, Tabriz, Islamic Republic of Iran Corresponding Author: Leila Safyari, Department of Operative and Esthetic Dentistry, Faculty of Dentistry, Tabriz University of Medical Science, Tabriz, Islamic Republic of Iran, e-mail: leilasafyari@gmail.com 10.5005/jp-journals-10015-1471

Comparison of Compressive Strength and Setting Time of Four Experimental Nanohybrid Mineral Trioxide Aggregates and Angelus Mineral Trioxide Aggregate