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Studies indicate that 3D power Doppler imaging can improve the ability to differenti ate benign from malignant ovarian masses, increasing significantly specificity and positive predictive value (PPV) in ovarian cancer detec tion. Therefore, the problem of low PPV in ultrasound-only strategies may be solved by introducing new 3D ultrasound technologies, used together in a secondary screening procedure. The possible role of 3D ultrasound and 3D power Doppler imaging in the early and accurate detection of ovarian cancer is under evaluation through Zagreb Ovarian Cancer Screening Trial.

Screening for Ovarian Cancer by Different Modes of Transvaginal Sonography